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Predicting Drug–Drug Interactions: An FDA Perspective

Pharmacokinetic drug interactions can lead to serious adverse events, and the evaluation of a new molecular entity’s drug–drug interaction potential is an integral part of drug development and regulatory review prior to its market approval. Alteration of enzyme and/or transporter activities involved...

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Detalhes bibliográficos
Main Authors: Zhang, Lei, Zhang, Yuanchao (Derek), Zhao, Ping, Huang, Shiew-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691466/
https://ncbi.nlm.nih.gov/pubmed/19418230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9106-3
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