Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy

BACKGROUND: The hematopoietic Granulocyte-Colony Stimulating Factor (G-CSF) plays a crucial role in controlling the number of neutrophil progenitor cells. Its function is mediated via the G-CSF receptor, which was recently found to be expressed also in the central nervous system. In addition, G-CSF...

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Hlavní autoři: Frank, Tobias, Schlachetzki, Johannes CM, Göricke, Bettina, Meuer, Katrin, Rohde, Gundula, Dietz, Gunnar PH, Bähr, Mathias, Schneider, Armin, Weishaupt, Jochen H
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691410/
https://ncbi.nlm.nih.gov/pubmed/19442279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-49
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