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A let-7 microRNA-binding site polymorphism in the KRAS 3′ UTR is associated with reduced survival in oral cancers

MicroRNA (miRNA)-binding site polymorphisms that could contribute to disease risk and prognosis are rapidly being identified and investigated as this genetic variation may have a potentially profound impact on human health. A recently described variant allele in the KRAS 3′ untranslated region that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Christensen, Brock C., Moyer, Benjamin J., Avissar, Michele, Ouellet, Lauren G., Plaza, Silvia L., McClean, Michael D., Marsit, Carmen J., Kelsey, Karl T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691138/
https://ncbi.nlm.nih.gov/pubmed/19380522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp099
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