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Evaluation of a Novel Therapeutic Approach to Treating Severe Pneumococcal Infection Using a Mouse Model

P4, a 28-amino-acid peptide, is a eukaryotic cellular activator that enhances specific in vitro opsonophagocytic killing of multiple bacterial pathogens. In a previous study, we successfully recreated this phenomenon in mice in vivo by using a two-dose regimen of P4 and pathogen-specific antibodies,...

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Detalhes bibliográficos
Main Authors: Melnick, Nikkol, Rajam, Gowrisankar, Carlone, George M., Sampson, Jacquelyn S., Ades, Edwin W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691041/
https://ncbi.nlm.nih.gov/pubmed/19386795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00120-09
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