Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells

BACKGROUND: Natalizumab is an antibody directed against integrin α4 that reduces disease activity in patients with multiple sclerosis (MS) by blocking migration of T and B cells into the CNS. The goal of this study was to characterize the effects of natalizumab treatment on cytokine production and e...

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Bibliografiske detaljer
Main Authors: Kivisäkk, P, Healy, B C., Viglietta, V, Quintana, F J., Hootstein, M A., Weiner, H L., Khoury, S J.
Format: Artigo
Sprog:Inglês
Udgivet: American Academy of Neurology 2009
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690969/
https://ncbi.nlm.nih.gov/pubmed/19487650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181a8266f
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