Increased isolevuglandin-modified proteins in glaucomatous astrocytes

PURPOSE: Lipid oxidation has been proposed to be a factor in the pathophysiology of glaucoma. We investigated whether elevated levels of isolevuglandin (iso[4]LGE(2)) protein adducts are associated with astrocytes derived from the glaucomatous optic nerve head. In addition, we examined whether the i...

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Main Authors: Govindarajan, Bharathi, Junk, Anna, Algeciras, Mabel, Salomon, Robert G., Bhattacharya, Sanjoy K.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690965/
https://ncbi.nlm.nih.gov/pubmed/19503745
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