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Functional Equivalency Inferred from “Authoritative Sources” in Networks of Homologous Proteins

A one-on-one mapping of protein functionality across different species is a critical component of comparative analysis. This paper presents a heuristic algorithm for discovering the Most Likely Functional Counterparts (MoLFunCs) of a protein, based on simple concepts from network theory. A key featu...

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Autori principali: Natarajan, Shreedhar, Jakobsson, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690840/
https://ncbi.nlm.nih.gov/pubmed/19521530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005898
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