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Formulation Design and Optimization of Novel Taste Masked Mouth-Dissolving Tablets of Tramadol Having Adequate Mechanical Strength

The purpose of this work was to develop novel taste masked mouth-dissolving tablets of tramadol that overcomes principle drawback of such formulation which is inadequate mechanical strength. Tramadol is an opioid analgesic used for the treatment of moderate to severe pain. Mouth-dissolving tablets o...

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Detalhes bibliográficos
Main Authors: Madgulkar, Ashwini R., Bhalekar, Mangesh R., Padalkar, Rahul R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690800/
https://ncbi.nlm.nih.gov/pubmed/19440844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9237-y
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