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Microemulsion-Based Vaginal Gel of Clotrimazole: Formulation, In Vitro Evaluation, and Stability Studies

The objective of the present investigation was to develop and evaluate microemulsion-based gel for the vaginal delivery of clotrimazole (CMZ). The solubility of CMZ in oils and surfactants was evaluated to identify components of the microemulsion. The ternary diagram was plotted to identify the area...

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Autors principals: Bachhav, Yogeshwar G., Patravale, Vandana B.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690796/
https://ncbi.nlm.nih.gov/pubmed/19381825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9233-2
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