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Anhydride Prodrug of Ibuprofen and Acrylic Polymers
The objective of this study was to synthesize anhydride prodrugs for carboxylic-acid-bearing agents such as non-steroidal anti-inflammatory drugs, shield the carboxylic acid group from irritative effects, and obtain sustained release patterns. Ibuprofen was used as a representative drug for anhydrid...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer US
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2690791/ https://ncbi.nlm.nih.gov/pubmed/19381828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9228-z |
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