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Anhydride Prodrug of Ibuprofen and Acrylic Polymers

The objective of this study was to synthesize anhydride prodrugs for carboxylic-acid-bearing agents such as non-steroidal anti-inflammatory drugs, shield the carboxylic acid group from irritative effects, and obtain sustained release patterns. Ibuprofen was used as a representative drug for anhydrid...

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Detalhes bibliográficos
Main Authors: Mizrahi, Boaz, Domb, Abraham J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690791/
https://ncbi.nlm.nih.gov/pubmed/19381828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9228-z
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