Hesperidin Gastroresistant Microparticles by Spray-Drying: Preparation, Characterization, and Dissolution Profiles

Gastroresistant microparticles for oral administration of hesperidin (Hd) were produced by spray-drying using cellulose acetate phthalate (CAP) as enteric polymer in different polymer/Hd weight ratio (1:1, 3:1, and 5:1), and a series of enhancers of the dissolution rate, such as sodium carboxymethyl...

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Bibliographic Details
Main Authors: Sansone, Francesca, Rossi, Alessandra, Del Gaudio, Pasquale, De Simone, Francesco, Aquino, Rita Patrizia, Lauro, Maria Rosaria
Format: Artigo
Language:Inglês
Published: Springer US 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690782/
https://ncbi.nlm.nih.gov/pubmed/19381835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9219-0
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