Cationic lipid/DNA complexes (JVRS-100) combined with influenza vaccine (Fluzone(®)) increases antibody response, cellular immunity, and antigenically drifted protection

Safe and effective adjuvants for influenza vaccines that could increase both the levels of neutralizing antibody, including against drifted viral subtypes, and T-cell immunity would be a major advance in vaccine design. The JVRS-100 adjuvant, consisting of DOTIM/cholesterol cationic liposome-DNA com...

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Bibliografske podrobnosti
Main Authors: Lay, Marla, Callejo, Bernadette, Chang, Stella, Hong, David K., Lewis, David B., Carroll, Timothy D, Matzinger, Shannon, Fritts, Linda, Miller, Christopher J, Warner, John F., Liang, Lily, Fairman, Jeffery
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690618/
https://ncbi.nlm.nih.gov/pubmed/19406188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.04.054
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