Circadian rhythm in rest and activity: a biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer

The rest/activity circadian rhythm (CircAct) reflects the function of the circadian timing system (CTS). In a prior single-institution study, the extent of CircAct perturbation independently predicted for survival and tumor response in 192 patients receiving chemotherapy for metastatic colorectal ca...

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Autors principals: Innominato, Pasquale F., Focan, Christian, Gorlia, Thierry, Moreau, Thierry, Garufi, Carlo, Waterhouse, Jim, Giacchetti, Sylvie, Coudert, Bruno, Iacobelli, Stefano, Genet, Dominique, Tampellini, Marco, Chollet, Philippe, Lentz, Marie-Ange, Mormont, Marie-Christine, Lévi, Francis, Bjarnason, Georg A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690615/
https://ncbi.nlm.nih.gov/pubmed/19470769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4747
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