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A dual role of Cdk2 in DNA damage response

Once it was believed that Cdk2 was the master regulator of S phase entry. Gene knockout mouse studies of cell cycle regulators revealed that Cdk2 is dispensable for S phase initiation and progression whereby Cdk1 can compensate for the loss of Cdk2. Nevertheless, recent evidence indicates that Cdk2...

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Detalhes bibliográficos
Main Authors: Satyanarayana, Ande, Kaldis, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690586/
https://ncbi.nlm.nih.gov/pubmed/19445729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-4-9
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