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Agrin in Alzheimer’s disease: Altered solubility and abnormal distribution within microvasculature and brain parenchyma

Agrin is a heparan sulfate proteoglycan that is widely expressed in neurons and microvascular basal lamina in the rodent and avian central nervous system. Agrin induces the differentiation of nerve-muscle synapses, but its function in either normal or diseased brains is not known. Alzheimer’s diseas...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Donahue, John E., Berzin, Tyler M., Rafii, Michael S., Glass, David J., Yancopoulos, George D., Fallon, Justin R., Stopa, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10339611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.11.6468
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