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Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection

Inflammatory caspases are important effectors of innate immunity. Caspase-12, of the inflammatory caspase subfamily, is expressed in all mammals tested to date, but has acquired deleterious mutation in humans. A single-nucleotide polymorphism introduces a premature stop codon in caspase-12 in the ma...

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Detalhes bibliográficos
Principais autores: Yeretssian, Garabet, Doiron, Karine, Shao, Wei, Leavitt, Blair R., Hayden, Michael R., Nicholson, Donald W., Saleh, Maya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690057/
https://ncbi.nlm.nih.gov/pubmed/19447924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813362106
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