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Peripheral tumors induce depressive-like behaviors and cytokine production and alter hypothalamic-pituitary-adrenal axis regulation

A strong and positive correlation exists between chronic disease and affective disorders, but the biological mechanisms underlying this relationship are not known. Here we show that rats with mammary cancer exhibit depression- and anxiety-like behaviors in the absence of overt sickness behaviors. Th...

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Hlavní autoři: Pyter, Leah M., Pineros, Vanessa, Galang, Jerome A., McClintock, Martha K., Prendergast, Brian J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689998/
https://ncbi.nlm.nih.gov/pubmed/19451634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811949106
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