Bladder hyperactivity and increased excitability of bladder afferent neurons associated with reduced expression of Kv1.4 α-subunit in rats with cystitis

Hyperexcitability of C-fiber bladder afferent pathways has been proposed to contribute to urinary frequency and bladder pain in chronic bladder inflammation including interstitial cystitis. However, the detailed mechanisms inducing afferent hyperexcitability after bladder inflammation are not fully...

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Autores principales: Hayashi, Yukio, Takimoto, Koichi, Chancellor, Michael B., Erickson, Kristin A., Erickson, Vickie L., Kirimoto, Tsukasa, Nakano, Koushi, de Groat, William C., Yoshimura, Naoki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
Materias:
Urogenital Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689836/
https://ncbi.nlm.nih.gov/pubmed/19279288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.91054.2008
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