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Excessive Ovarian Production of Nerve Growth Factor Facilitates Development of Cystic Ovarian Morphology in Mice and Is a Feature of Polycystic Ovarian Syndrome in Humans

Although ovarian nerve growth factor (NGF) facilitates follicular development and ovulation, an excess of the neurotrophin in the rodent ovary reduces ovulatory capacity and causes development of precystic follicles. Here we show that ovarian NGF production is enhanced in patients with polycystic ov...

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Bibliografiska uppgifter
Huvudupphovsmän: Dissen, Gregory A., Garcia-Rudaz, Cecilia, Paredes, Alfonso, Mayer, Christine, Mayerhofer, Artur, Ojeda, Sergio R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Endocrine Society 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689806/
https://ncbi.nlm.nih.gov/pubmed/19264868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1575
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