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Statistical Model to Analyze Quantitative Proteomics Data Obtained by (18)O/(16)O Labeling and Linear Ion Trap Mass Spectrometry: Application to the Study of Vascular Endothelial Growth Factor-induced Angiogenesis in Endothelial Cells

Statistical models for the analysis of protein expression changes by stable isotope labeling are still poorly developed, particularly for data obtained by (16)O/(18)O labeling. Besides large scale test experiments to validate the null hypothesis are lacking. Although the study of mechanisms underlyi...

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Detalhes bibliográficos
Main Authors: Jorge, Inmaculada, Navarro, Pedro, Martínez-Acedo, Pablo, Núñez, Estefanía, Serrano, Horacio, Alfranca, Arántzazu, Redondo, Juan Miguel, Vázquez, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689778/
https://ncbi.nlm.nih.gov/pubmed/19181660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800260-MCP200
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