Simultaneous GC–EI-MS Determination of Δ(9)-Tetrahydrocannabinol, 11-Hydroxy-Δ(9)-Tetrahydrocannabinol, and 11-nor-9-Carboxy-Δ(9)-Tetrahydrocannabinol in Human Urine Following Tandem Enzyme-Alkaline Hydrolysis

A sensitive and specific method for extraction and quantification of Δ(9)-tetrahydrocannabinol (THC), 11-hydroxy-Δ(9)-tetrahydrocannabinol (11-OH-THC), and 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol (THCCOOH) in human urine was developed and fully validated. To ensure complete hydrolysis of conjugat...

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Hauptverfasser: Abraham, Tsadik T., Lowe, Ross H., Pirnay, Stephane O., Darwin, William D., Huesti, Marilyn A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689549/
https://ncbi.nlm.nih.gov/pubmed/17988462
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