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gp120-Induced Neurotoxicity in Hippocampal Pyramidal Neuron Cultures: Protective Action of TGF-β1

We found that TGF-β1, a cytokine that previously has been reported to have neuroprotective effects, was able to prevent the toxicity induced by the HIV-1 coat protein gp120 in hippocampal pyramidal neuron cultures. In the presence of glia, gp120 induced time- and dose-dependent cell death, which was...

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Bibliographic Details
Main Authors: Meucci, Olimpia, Miller, Richard J.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689548/
https://ncbi.nlm.nih.gov/pubmed/8753870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-13-04080.1996
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