Predictive value of Ki67 and p53 in locally advanced rectal cancer: Correlation with thymidylate synthase and histopathological tumor regression after neoadjuvant 5-FU-based chemoradiotherapy

AIM: To investigate the predictive value of Ki67 and p53 and their correlation with thymidylate synthase (TS) gene expression in a rectal cancer patient cohort treated according to a standardized recommended neoadjuvant treatment regimen. METHODS: Formalin fixed, paraffin embedded pre-therapeutical...

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Autors principals: Jakob, Christiane, Liersch, Torsten, Meyer, Wolfdietrich, Becker, Heinz, Baretton, Gustavo B, Aust, Daniela E
Format: Artigo
Idioma:Inglês
Publicat: The WJG Press and Baishideng 2008
Matèries:
Colorectal Cancer
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689409/
https://ncbi.nlm.nih.gov/pubmed/18286688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.1060
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