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Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness

Recent data from transgenic mice suggest that orexin plays an important role in the ventilatory response to CO(2) during wakefulness. We hypothesized that orexin receptor-1 (OX(1)R) in the retrotrapezoid nucleus (RTN) contributes to chemoreception. In unanaesthetized rats, we measured ventilation us...

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Hlavní autoři: Dias, Mirela Barros, Li, Aihua, Nattie, Eugene E
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689343/
https://ncbi.nlm.nih.gov/pubmed/19273574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.168260
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