Transcriptional signatures of Itk-deficient CD3(+), CD4(+ )and CD8(+ )T-cells

BACKGROUND: The Tec-family kinase Itk plays an important role during T-cell activation and function, and controls also conventional versus innate-like T-cell development. We have characterized the transcriptome of Itk-deficient CD3(+ )T-cells, including CD4(+ )and CD8(+ )subsets, using Affymetrix mi...

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Autors principals: Blomberg, K Emelie M, Boucheron, Nicole, Lindvall, Jessica M, Yu, Liang, Raberger, Julia, Berglöf, Anna, Ellmeier, Wilfried, Smith, CI Edvard
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689280/
https://ncbi.nlm.nih.gov/pubmed/19450280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-233
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