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Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

A diverse array of infectious agents, including prions and certain neurotropic viruses, bind to the laminin receptor (LR), and this determines tropism to the CNS. Bacterial meningitis in childhood is almost exclusively caused by the respiratory tract pathogens Streptococcus pneumoniae, Neisseria men...

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Detalhes bibliográficos
Main Authors: Orihuela, Carlos J., Mahdavi, Jafar, Thornton, Justin, Mann, Beth, Wooldridge, Karl G., Abouseada, Noha, Oldfield, Neil J., Self, Tim, Ala’Aldeen, Dlawer A.A., Tuomanen, Elaine I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689107/
https://ncbi.nlm.nih.gov/pubmed/19436113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36759
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