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Gfi1 integrates progenitor versus granulocytic transcriptional programming
In patients with severe congenital neutropenia (SCN) and mice with growth factor independent-1 (Gfi1) loss of function, arrested myeloid progenitors accumulate, whereas terminal granulopoiesis is blocked. One might assume that Gfi-null progenitors accumulate because they lack the ability to differen...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689047/ https://ncbi.nlm.nih.gov/pubmed/19346496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-179747 |
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