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The breast cancer somatic 'muta-ome': tackling the complexity

Acquired somatic mutations are responsible for approximately 90% of breast tumours. However, only one somatic aberration, amplification of the HER2 locus, is currently used to define a clinical subtype, one that accounts for approximately 10% to 15% of breast tumours. In recent years, a number of mu...

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Hlavní autoři: Teschendorff, Andrew E, Caldas, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688941/
https://ncbi.nlm.nih.gov/pubmed/19344493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2236
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