Melanopsin as a Sleep Modulator: Circadian Gating of the Direct Effects of Light on Sleep and Altered Sleep Homeostasis in Opn4(−/−) Mice

Light influences sleep and alertness either indirectly through a well-characterized circadian pathway or directly through yet poorly understood mechanisms. Melanopsin (Opn4) is a retinal photopigment crucial for conveying nonvisual light information to the brain. Through extensive characterization o...

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Detalhes bibliográficos
Main Authors: Tsai, Jessica W., Hannibal, Jens, Hagiwara, Grace, Colas, Damien, Ruppert, Elisabeth, Ruby, Norman F., Heller, H. Craig, Franken, Paul, Bourgin, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688840/
https://ncbi.nlm.nih.gov/pubmed/19513122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000125
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