Protein Kinase Cδ Regulates Ethanol Intoxication and Enhancement of GABA-Stimulated Tonic Current

Ethanol alters the distribution and abundance of PKCδ in neural cell lines. Here we investigated whether PKCδ also regulates behavioral responses to ethanol. PKCδ(−/−) mice showed reduced intoxication when administered ethanol and reduced ataxia when administered the nonselective GABA(A) receptor ag...

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Detalhes bibliográficos
Main Authors: Choi, Doo-Sup, Wei, Weizheng, Deitchman, J. Kevin, Kharazia, Viktor N., Lesscher, Heidi M. B., McMahon, Thomas, Wang, Dan, Qi, Zhan-Heng, Sieghart, Werner, Zhang, Chao, Shokat, Kevan M., Mody, Istvan, Messing, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688726/
https://ncbi.nlm.nih.gov/pubmed/19005054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3156-08.2008
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