AHR-Enhancing γδ T Cells Develop in Normal Untreated Mice and Fail to Produce IL-4/13, Unlike TH2 Cells and NKT Cells

Allergic airway hyperresponsiveness (AHR) in OVA-sensitized and challenged mice, mediated by allergen-specific Th2 cells and Th2-like iNKT cells, develops under the influence of enhancing and inhibitory γδ T cells. The AHR-enhancing cells belong to the Vγ1(+) γδ T cell subset, cells that are capable...

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Main Authors: Jin, Niyun, Roark, Christina L., Miyahara, Nobuaki, Taube, Christian, Aydintug, M. Kemal, Wands, JM, Huang, Yafei, Hahn, Youn-Soo, Gelfand, Erwin W., O’Brien, Rebecca L., Born, Willi K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688721/
https://ncbi.nlm.nih.gov/pubmed/19201853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803280
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