Topoisomerase I and IIα protein expression in primary colorectal cancer and recurrences following 5-fluorouracil-based adjuvant chemotherapy

PURPOSE: Human DNA topoisomerases I and II (topo-I and -II) are essential for vital cellular processes such as DNA replication, transcription, translation, recombination, and repair. In the present study, we correlate topo-I and -II expression and outcome after chemotherapy in primary and relapsed c...

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Autores principales: Tsavaris, Nicolas, Lazaris, Andreas, Kosmas, Christos, Gouveris, Panagiotis, Kavantzas, Nikolaos, Kopterides, Petros, Papathomas, Thomas, Arapogiannis, George, Zorzos, Haralambos, Kyriakou, Vassiliki, Patsouris, Efstathios
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2008
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688619/
https://ncbi.nlm.nih.gov/pubmed/19083133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0886-4
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