CRH haplotype predicts CSF CRH, HPA axis activity, temperament, and alcohol consumption in rhesus macaques

CONTEXT: Both stress-reactive and novelty-seeking individuals are susceptible to alcohol use disorders. Variation in stress reactivity, exploration, and response to novelty have been attributed to differences in corticotropin-releasing hormone (CRH) system function. As such, CRH gene variation may i...

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Main Authors: Barr, Christina S., Dvoskin, Rachel L., Yuan, Qiaoping, Lipsky, Robert H., Gupte, Manisha, Hu, Xian, Zhou, Zhifeng, Schwandt, Melanie L., Lindell, Stephen G., McKee, Megan, Becker, Michelle L., Kling, Mitchel A., Gold, Phillip W., Higley, Dee, Heilig, Markus, Suomi, Stephen J., Goldman, David
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688441/
https://ncbi.nlm.nih.gov/pubmed/18678798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archpsyc.65.8.934
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