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Interactive sequences in the molecular chaperone, human αB crystallin modulate the fibrillation of amyloidogenic proteins

Multiple interactive domains are involved in the activity of the stress protein, αB crystallin that protects against the unfolding, aggregation, and toxicity of amyloidogenic proteins. Five peptides corresponding to the interactive sequences (41)STSLSPFYLRPPSFLRAP(58), (73)DRFSVNLDVKHFS(85), (101)HG...

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Autori principali: Ghosh, Joy G., Houck, Scott A., Clark, John I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688400/
https://ncbi.nlm.nih.gov/pubmed/18162431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2007.10.035
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