Bruton’s tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding protein

Bruton’s tyrosine kinase (Btk) is a cytoplasmic tyrosine kinase that is crucial for human and murine B cell development, and its deficiency causes human X-linked agammaglobulinemia and murine X-linked immunodeficiency. In this report, we describe the function of the Btk-binding protein Sab (SH3-doma...

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Hlavní autoři: Yamadori, Tomoki, Baba, Yoshihiro, Matsushita, Masato, Hashimoto, Shoji, Kurosaki, Mari, Kurosaki, Tomohiro, Kishimoto, Tadamitsu, Tsukada, Satoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC26883/
https://ncbi.nlm.nih.gov/pubmed/10339589
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