Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus

INTRODUCTION: The high-affinity receptor for IgG Fcγ/CD64 is critical for the development of lupus nephritis (LN). Cross-linking Fc receptor on recruited monocytes by IgG-containing immune complexes is a key step in immune-complex-mediated nephritis in systemic lupus erythematosus (SLE). The goal of...

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Detalhes bibliográficos
Principais autores: Li, Yi, Lee, Pui Y, Sobel, Eric S, Narain, Sonali, Satoh, Minoru, Segal, Mark S, Reeves, Westley H, Richards, Hanno B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688236/
https://ncbi.nlm.nih.gov/pubmed/19144150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2590
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