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Randomized controlled trial design in rheumatoid arthritis: the past decade

Much progress has occurred over the past decade in rheumatoid arthritis trial design. Recognized challenges have led to the establishment of a clear regulatory pathway to demonstrate efficacy of a new therapeutic. The use of pure placebo beyond 12 to 16 weeks has been demonstrated to be unethical an...

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Detalhes bibliográficos
Main Authors: Strand, Vibeke, Sokolove, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688216/
https://ncbi.nlm.nih.gov/pubmed/19232061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2555
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