Hydroxyethylstarch impairs renal function and induces interstitial proliferation, macrophage infiltration and tubular damage in an isolated renal perfusion model

INTRODUCTION: The aim of the study was to evaluate some of the underlying pathomechanisms of hydroxyethylstarch (HES) induced adverse effects on renal function using 24 porcine kidneys in an isolated perfusion model over six hours. METHODS: Infusion of either 10% HES 200/0.5, 6% HES 130/0.42 or Ring...

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Detalhes bibliográficos
Main Authors: Hüter, Lars, Simon, Tim-Philipp, Weinmann, Lenard, Schuerholz, Tobias, Reinhart, Konrad, Wolf, Gunter, Amann, Kerstin Ute, Marx, Gernot
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688141/
https://ncbi.nlm.nih.gov/pubmed/19239718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7726
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