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Molecular Evolutionary Consequences of Niche Restriction in Francisella tularensis, a Facultative Intracellular Pathogen

Francisella tularensis is a potent mammalian pathogen well adapted to intracellular habitats, whereas F. novicida and F. philomiragia are less virulent in mammals and appear to have less specialized lifecycles. We explored adaptations within the genus that may be linked to increased host association...

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Detalhes bibliográficos
Main Authors: Larsson, Pär, Elfsmark, Daniel, Svensson, Kerstin, Wikström, Per, Forsman, Mats, Brettin, Thomas, Keim, Paul, Johansson, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688086/
https://ncbi.nlm.nih.gov/pubmed/19521508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000472
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