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Stem cells are dispensable for lung homeostasis but restore airways after injury

Local tissue stem cells have been described in airways of the lung but their contribution to normal epithelial maintenance is currently unknown. We therefore developed aggregation chimera mice and a whole-lung imaging method to determine the relative contributions of progenitor (Clara) and bronchiol...

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Detalhes bibliográficos
Main Authors: Giangreco, Adam, Arwert, Esther N., Rosewell, Ian R., Snyder, Joshua, Watt, Fiona M., Stripp, Barry R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687999/
https://ncbi.nlm.nih.gov/pubmed/19478060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900668106
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