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Constrained mixture estimation for analysis and robust classification of clinical time series

Motivation: Personalized medicine based on molecular aspects of diseases, such as gene expression profiling, has become increasingly popular. However, one faces multiple challenges when analyzing clinical gene expression data; most of the well-known theoretical issues such as high dimension of featu...

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Detalhes bibliográficos
Main Authors: Costa, Ivan G., Schönhuth, Alexander, Hafemeister, Christoph, Schliep, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687976/
https://ncbi.nlm.nih.gov/pubmed/19478017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp222
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