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Predicting functionality of protein–DNA interactions by integrating diverse evidence

Chromatin immunoprecipitation (ChIP-chip) experiments enable capturing physical interactions between regulatory proteins and DNA in vivo. However, measurement of chromatin binding alone is not sufficient to detect regulatory interactions. A detected binding event may not be biologically relevant, or...

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Autors principals: Ucar, Duygu, Beyer, Andreas, Parthasarathy, Srinivasan, Workman, Christopher T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687967/
https://ncbi.nlm.nih.gov/pubmed/19477979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp213
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