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Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors

INTRODUCTION: High expression of total HER2 protein confers poor prognosis for breast cancer patients. HER2 is a member of the HER family consisting of four receptors, HER1 to HER4. HER receptor activity is regulated by a variety of mechanisms, and phosphorylation of the C-terminal part of the HER r...

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מידע ביבליוגרפי
Main Authors: Frogne, Thomas, Laenkholm, Anne-Vibeke, Lyng, Maria B, Henriksen, Katrine Lütken, Lykkesfeldt, Anne E
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687716/
https://ncbi.nlm.nih.gov/pubmed/19239686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2230
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