A method to assess the clinical significance of unclassified variants in the BRCA1 and BRCA2 genes based on cancer family history

INTRODUCTION: Unclassified variants (UVs) in the BRCA1/BRCA2 genes are a frequent problem in counseling breast cancer and/or ovarian cancer families. Information about cancer family history is usually available, but has rarely been used to evaluate UVs. The aim of the present study was to identify w...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Gómez García, Encarna B, Oosterwijk, Jan C, Timmermans, Maarten, van Asperen, Christi J, Hogervorst, Frans BL, Hoogerbrugge, Nicoline, Oldenburg, Rogier, Verhoef, Senno, Dommering, Charlotte J, Ausems, Margreet GEM, van Os, Theo AM, van der Hout, Annemarie H, Ligtenberg, Marjolijn, van den Ouweland, Ans, van der Luijt, Rob B, Wijnen, Juul T, Gille, Jan JP, Lindsey, Patrick J, Devilee, Peter, Blok, Marinus J, Vreeswijk, Maaike PG
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687711/
https://ncbi.nlm.nih.gov/pubmed/19200354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2223
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы