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Small local variations in B-form DNA lead to a large variety of global geometries which can accommodate most DNA-binding protein motifs
BACKGROUND: An important question of biological relevance is the polymorphism of the double-helical DNA structure in its free form, and the changes that it undergoes upon protein-binding. We have analysed a database of free DNA crystal structures to assess the inherent variability of the free DNA st...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2687451/ https://ncbi.nlm.nih.gov/pubmed/19393049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-9-24 |
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