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Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells

BACKGROUND: Although the MMP-2 promoter lacks a canonical progesterone response element (PRE), the hormone inhibits MMP-2 expression and is part of treatment protocols in gynecological invasive pathologies, including endometriosis and endometrial hyperplasia. This study aimed to explore the mechanis...

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Detalhes bibliográficos
Main Authors: Goldman, Shlomit, Lovett, David H, Shalev, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687445/
https://ncbi.nlm.nih.gov/pubmed/19426551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-7-41
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