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Analysis of the Varicella-Zoster Virus IE62 N-Terminal Acidic Transactivating Domain and Its Interaction with the Human Mediator Complex

The varicella-zoster virus major transactivator, IE62, contains a potent N-terminal acidic transcriptional activation domain (TAD). Our experiments revealed that the minimal IE62 TAD encompasses amino acids (aa) 19 to 67. We showed that the minimal TAD interacts with the human Mediator complex. Site...

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Autors principals: Yamamoto, Shinobu, Eletsky, Alexander, Szyperski, Thomas, Hay, John, Ruyechan, William T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687382/
https://ncbi.nlm.nih.gov/pubmed/19357160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00054-09
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