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Identification of migR, a Regulatory Element of the Francisella tularensis Live Vaccine Strain iglABCD Virulence Operon Required for Normal Replication and Trafficking in Macrophages

Francisella tularensis, the etiological agent of tularemia, is capable of infecting a wide range of animals and causes a severe, lethal disease in humans. The pathogen evades killing by cells of the innate immune system utilizing genes encoding a pathogenicity island, including iglABCD, and instead...

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Autors principals: Buchan, Blake W., McCaffrey, Ramona L., Lindemann, Stephen R., Allen, Lee-Ann H., Jones, Bradley D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687360/
https://ncbi.nlm.nih.gov/pubmed/19349423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00229-09
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