Загрузка...

Bacillus anthracis Edema Toxin Suppresses Human Macrophage Phagocytosis and Cytoskeletal Remodeling via the Protein Kinase A and Exchange Protein Activated by Cyclic AMP Pathways

Bacillus anthracis, the etiological agent of anthrax, is a gram-positive spore-forming bacterium. It produces edema toxin (EdTx), a powerful adenylate cyclase that increases cyclic AMP (cAMP) levels in host cells. Because other cAMP-increasing agents inhibit key macrophage (MΦ) functions, such as ph...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Yeager, Linsey A., Chopra, Ashok K., Peterson, Johnny W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687349/
https://ncbi.nlm.nih.gov/pubmed/19307216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00905-08
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!