Omeprazole Antagonizes Virulence and Inflammation in Salmonella enterica-Infected RAW264.7 Cells

The proton pump inhibitor omeprazole reduced the intracellular replication of Salmonella enterica serovar Typhimurium in RAW264.7 cells without affecting bacterial growth in vitro or the viability of the host cells. The mechanism was bacteriostatic and interfered with replication mediated by the vir...

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Bibliographic Details
Main Authors: Puiac, Speranta, Negrea, Aurel, Richter-Dahlfors, Agneta, Plant, Laura, Rhen, Mikael
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687253/
https://ncbi.nlm.nih.gov/pubmed/19307359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01483-08
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